For decades, physicians have hunted each dieter's dream of weight reduction: a pill that may pare away the pounds without any harmful effects. Their pursuit is an acknowledgment that losing weight and keeping it off isn't only a matter of willpower, of resisting the siren call of this ice cream in the fridge. New research has shown that weight reduction changes the body and brain. And even if we starve ourselves thin, we often can't undo those adjustments. So we just slowly pack the pounds back on because our brains believe we need them.
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