Oxycodone is an extremely potent opioid painkiller and must be consumed precisely as directed to reduce the risk of adverse side consequences. In order to minimize the possibility of adverse consequences, make sure to use the pill in the same time throughout the throughout the day taking it in whole along with a drink of fluid. Drinking the tablet along with meals could help avoid stomach discomfort or nausea. Stay clear of alcohol and other sedating medication, because they could be dangerously causing drowsiness, or breathing difficulties. Avoid chewing or crushing extended-release tablets because this could release too much of the drug in one go. Start by taking the the lowest dose that is effective and then follow the doctor's guidelines carefully. Constipation or dizziness are not uncommon, therefore being well-hydrated and moving frequently can be beneficial.