Eliot and Jackie met in High School on the magical (terrible) peninsula known as "Long Island," and have been war buddies ever since. Each week on Best Friends, However, you'll hear them duke it out over something they don't have in common, from Eliot's excessive love for the Golden Girls to Jackie's almost non-existant knowledge of pop culture to Eliot's completely non-existent knowledge of female anatomy. Each week Eliot and Jackie tell stories, take quizzes, thoroughly embarrass each other, and learn a little bit more about "friendship".