Combined with novel insecticides for mosquitoes and vaccines and anti-pathogen drugs, such techniques could significantly decrease mosquito populations and incidence of diseases they transmit. Both significant vectors of the most devastating mosquito-borne diseases to humans are Aedes aegypti - the principal vector for dengue, yellow fever, chikungunya virus, and, lately, Zika virus - and Anopheles gambiae, the vector for malaria. Juvenile hormone, which occurs only in bugs, regulates this stage.

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