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Herpes simplex is one of the most pathogenic diseases that causes an outbreak of sores and blisters on the mouth and genital area. About 25% of Americans have this disease, in the active or inactive form. 1 in 2 Americans is infected with HSV-1 (Herpes Simplex Virus) or otherwise known as oral herpes. And 1 in 8 Americans is infected with HSV-2 or genital herpes. Herpes was considered incurable back in time, but now, many types of medications are available to treat herpes.