- 1 year ago
Brain tumors can be among the most challenging cancers to treat. The blood-brain barrier, a natural defense mechanism that shields the brain from harm, can also prevent cancer treatments from reaching tumors.
“It can be difficult to get treatments effectively into the brain,” says David Reardon, MD, clinical director of Dana-Farber’s Center for Neuro-Oncology. However, he adds that new immunotherapy treatments may be able to get through the blood-brain barrier and effectively reach tumors.
“We know the immune system can get into the brain to fight infections and inflammatory conditions,” explains Reardon. “Our current research is moving forward to a level where we’re critically confirming that these immunotherapy drugs are getting into the brain and making a difference.”
In this Cancer Conversations podcast episode, Reardon discusses immunotherapy, precision medicine, and other new approaches to brain tumor treatment with Patrick Wen, MD, director of the Center for Neuro-Oncology.