At least 59 people have been killed and another 527 injured in a mass shooting at a concert in Las Vegas.
64-year-old Stephen Paddock, opened fire on an open-air music festival from the 32nd floor of a nearby hotel.
President Donald Trump described the attack as "pure evil."
We have the latest from Las Vegas.
Also on the programme, why the number of foreign applicants to US Business Schools is falling, a warning that markets aren't paying enough attention to geopolitical events when it comes to oil prices, and the US scientists honoured with the Nobel Prize for their work looking at the human body clock.
Lucy Burton is joined throughout the programme from San Francisco by Alison Van Diggelen, the host of radio programme Fresh Dialogues and Simon Littlewood, President of ACG consulting group in Singapore. They'll also be joined from Hong Kong by the BBC's Juliana Liu.
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